产品
编 号：F753103
分子式：C26H19N5O2
分子量：433.46
分子式：C26H19N5O2
分子量：433.46
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CAS No: 2475658-75-2
产品详情
生物活性：
HIV-1 inhibitor-24 (compound S-12a) is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 9.5 nM. HIV-1 inhibitor-24 has high antiretroviral activity against WT HIV-1 with an EC50 of 1.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 9.07 μM in MT-4 cells. HIV-1 inhibitor-24 is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety.
体内研究：
HIV-1 inhibitor-24 (2 g/kg; IG; single dosage) is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety.Animal Model:Mice
Dosage:2 g/kg
Administration:IG; single dosage
Result:Exhibited well tolerance at a dose of 2 g/kg in mice and a significant cardiovascular safety.
HIV-1 inhibitor-24 (compound S-12a) is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 9.5 nM. HIV-1 inhibitor-24 has high antiretroviral activity against WT HIV-1 with an EC50 of 1.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 9.07 μM in MT-4 cells. HIV-1 inhibitor-24 is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety.
体内研究：
HIV-1 inhibitor-24 (2 g/kg; IG; single dosage) is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety.Animal Model:Mice
Dosage:2 g/kg
Administration:IG; single dosage
Result:Exhibited well tolerance at a dose of 2 g/kg in mice and a significant cardiovascular safety.
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