产品
编 号:F753083
分子式:C13H15ClN2O
分子量:250.72
产品类型
结构图
CAS No: 2470969-89-0
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产品详情
生物活性:
SIRT1-IN-2 (compound 3h) is a potent and selective SIRT1 (silent information regulator 1) inhibitor, with an IC50 of 1.6 μM.
体外研究:
SIRT1-IN-2 (compound 3h) (0-100 μM, 48 h) inhibits the proliferation of Human cancer cell lines including K562, HCT-116, HepG2, A549, and MCF-7, and shows significantly less cytotoxic on 293T cells and HUVEC.