产品
编 号:F753080
分子式:C35H36F2N6O6S
分子量:706.76
产品类型
结构图
CAS No: 2470807-67-9
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产品详情
生物活性:
Multi-kinase-IN-1 (Compound 11k) is a potent kinase inhibitor with antitumor activity. Multi-kinase-IN-1 induces cell apoptosis, and can be studied for colorectal cancer.
体外研究:
Multi-kinase-IN-1 (Compound 11k) (0-5 μg/mL, 0-72 h) induces antiproliferation and cytotoxicity in a dose- and time-dependent manner in HT-29 cells, and is much less toxic to normal colorectal mucosa epithelial cells.Multi-kinase-IN-1 (0-3 μg/mL, 0-72 h) induces cell apoptosis in a time- and dose-dependent manner.Multi-kinase-IN-1 (0-3 μg/mL, 48 h) slightly induces cell cycle arrest in G2/M phase.