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编 号:F752971
分子式:C14H12ClN3O2S2
分子量:353.85
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生物活性:
CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. CDK1/Cyc B-IN-1 triggers apoptosis and G2/M cell cycle arrest. CDK1/Cyc B-IN-1 shows broad-spectrum cytotoxic action against cancer cell lines.

体外研究:
CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC50 values of 5.33 ± 0.69 μM and 21.69 ± 1.04 μM against HCT-116 and WI-38, respectively.
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