产品
编 号:F752958
分子式:C24H31ClN6O2
分子量:470.99
产品类型
结构图
CAS No: 2459489-51-9
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产品详情
生物活性:
AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer.
体外研究:
AKT-IN-13 (compound 4b) displays good potency in the LNCap cell line with an IC50 value of 103 nM and a high free fraction with 51.3% human plasma protein binding (PPB).