产品
编 号：F752947
分子式：C25H23N7O2
分子量：453.5
分子式：C25H23N7O2
分子量：453.5
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CAS No: 2458163-99-8
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生物活性：
PI3K-IN-35 (Compound 6l) is a highly selective PI3K inhibitor with IC50 values of 13.98, 7.22 and 10.94 μM for PI3K-α、PI3K-β and PI3K-δ, respectively. PI3K-IN-35 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-35 can be used in leukemia research.
体外研究：
PI3K-IN-35 (Compound 6l) (10 μM, 48 hours) possess potent antiproliferative activity can inhibit proliferation of Leukemia SR cell lines in vitro.PI3K-IN-35 (Compound 6l) induces cell cycle arrest toward the G2-M phase (41.61%) and leads to DNA synthesis and apoptosis.PI3K-IN-35 (Compound 6l) (10 μM, 48 hours) results in apoptotic with 16.98% of cells in the early and latest age.
PI3K-IN-35 (Compound 6l) is a highly selective PI3K inhibitor with IC50 values of 13.98, 7.22 and 10.94 μM for PI3K-α、PI3K-β and PI3K-δ, respectively. PI3K-IN-35 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-35 can be used in leukemia research.
体外研究：
PI3K-IN-35 (Compound 6l) (10 μM, 48 hours) possess potent antiproliferative activity can inhibit proliferation of Leukemia SR cell lines in vitro.PI3K-IN-35 (Compound 6l) induces cell cycle arrest toward the G2-M phase (41.61%) and leads to DNA synthesis and apoptosis.PI3K-IN-35 (Compound 6l) (10 μM, 48 hours) results in apoptotic with 16.98% of cells in the early and latest age.
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