产品
编 号：F752945
分子式：C23H21BrN6O2
分子量：493.36
分子式：C23H21BrN6O2
分子量：493.36
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CAS No: 2458163-92-1
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生物活性：
PI3K-IN-33 (Compound 6e) is a highly selective PI3K inhibitor with IC50 values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-33 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-33 can be used in leukemia research.
体外研究：
PI3K-IN-33 (Compound 6e) (10 μM, 48 hours) possess potent antiproliferative activity can inhibit proliferation of Leukemia SR cell lines in vitro.PI3K-IN-33 (Compound 6e) induces cell cycle arrest toward the G2-M phase (30.3%) and leads to DNA synthesis and apoptosis.PI3K-IN-33 (Compound 6e) (10 μM, 48 hours) results in apoptotic with 12.13% of cells in the early and latest age.
PI3K-IN-33 (Compound 6e) is a highly selective PI3K inhibitor with IC50 values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-33 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-33 can be used in leukemia research.
体外研究：
PI3K-IN-33 (Compound 6e) (10 μM, 48 hours) possess potent antiproliferative activity can inhibit proliferation of Leukemia SR cell lines in vitro.PI3K-IN-33 (Compound 6e) induces cell cycle arrest toward the G2-M phase (30.3%) and leads to DNA synthesis and apoptosis.PI3K-IN-33 (Compound 6e) (10 μM, 48 hours) results in apoptotic with 12.13% of cells in the early and latest age.
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