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编 号:F752940
分子式:C25H15ClF3N5O3
分子量:525.87
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生物活性:
CDK8-IN-10 (compound 2) is a potent, selective cyclin-dependent kinase (CDK8) inhibitor with an IC50 value of 8.25 nM. CDK8-IN-10 can be used for research of cancer.

体外研究:
CDK8-IN-10 (compound 2; 8 h; SW620 cells) reduces phosphorylation of CDK8 substrate STAT1 in cells with an IC50 value of 1.3 μM.
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