产品
编 号：F752931
分子式：C21H19N3O2
分子量：345.39
分子式：C21H19N3O2
分子量：345.39
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CAS No: 2456315-41-4
产品详情
生物活性：
VEGFR-2-IN-19 (Compound 15b) is a potent VEGFR2 inhibitor. VEGFR-2-IN-19 induces cell apoptosis and increases intracellular reactive oxygen species level. VEGFR-2-IN-19 can be used as an anticancer agent.
体外研究：
VEGFR-2-IN-19 (Compound 15b) (0-100 μM, 48 h) shows antiproliferative activity against cancer cells.VEGFR-2-IN-19 (0-10 μM, 48 h) inhibits the phosphorylation of VEGFR2 and the Raf/MEK/ERK signaling pathway, induces cell apoptosis, and arrests cell cycle at G0/G1 phase in HT-29 cells.VEGFR-2-IN-19 (0-10 μM, 12 h) increases intracellular reactive oxygen species level in HT-29 cells.
VEGFR-2-IN-19 (Compound 15b) is a potent VEGFR2 inhibitor. VEGFR-2-IN-19 induces cell apoptosis and increases intracellular reactive oxygen species level. VEGFR-2-IN-19 can be used as an anticancer agent.
体外研究：
VEGFR-2-IN-19 (Compound 15b) (0-100 μM, 48 h) shows antiproliferative activity against cancer cells.VEGFR-2-IN-19 (0-10 μM, 48 h) inhibits the phosphorylation of VEGFR2 and the Raf/MEK/ERK signaling pathway, induces cell apoptosis, and arrests cell cycle at G0/G1 phase in HT-29 cells.VEGFR-2-IN-19 (0-10 μM, 12 h) increases intracellular reactive oxygen species level in HT-29 cells.
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