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编 号:F752913
分子式:C28H23N3O6S
分子量:529.56
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生物活性:
VEGFR-2-IN-24 is a potent VEGFR-2 inhibitor with IC50 value of 0.22 μM. VEGFR-2-IN-24 can be used for tumor research.

体外研究:
VEGFR-2-IN-24 (Compound 8f) (0-1000 μM, 72 hours; human tumor cell lines) exerts the most potent antitumor activities against human cancer cell lines.VEGFR-2-IN-24 (Compound 8f) (0-1000 μM, 72 hours; human tumor cell lines) displays the highest anticancer activities with IC50 values of 11.19, 8.99 and 7.10 μM for HepG2, HCT-116 and MCF-7 cell lines, respectively.VEGFR-2-IN-24 (Compound 8f) (0-300 μg/mL, 5 min) remarkably exhibits VEGFR-2 inhibition with IC50 value of 0.22 μM.
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