产品
编 号：F752870
分子式：C68H90N6O14S
分子量：1247.54
分子式：C68H90N6O14S
分子量：1247.54
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规格
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是否有货
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CAS No: 2451573-87-6
产品详情
生物活性：
dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader.
体外研究：
dTAGV-1-NEG (1-10 μM; 24 h) not induces the degradation of FKBP12F36V-Nluc on 293FT FKBP12F36V-Nluc or FKBP12WT-Nluc cells.dTAGV-1-NEG (500 nM; 24 h) dose not induce the degradation of KRASG12V protein in PATU-8902 FKBP12F36V-KRASG12V and KRAS?/? cells.
dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader.
体外研究：
dTAGV-1-NEG (1-10 μM; 24 h) not induces the degradation of FKBP12F36V-Nluc on 293FT FKBP12F36V-Nluc or FKBP12WT-Nluc cells.dTAGV-1-NEG (500 nM; 24 h) dose not induce the degradation of KRASG12V protein in PATU-8902 FKBP12F36V-KRASG12V and KRAS?/? cells.
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