产品
编 号:F752844
分子式:C20H21N7S
分子量:391.49
产品类型
结构图
CAS No: 2447602-44-8
联系客服
产品详情
生物活性:
GlcN-6-P Synthase-IN-1 (Compound 4d) is a Glucosamine-6-phosphate (GlcN-6-P) synthase inhibitor with an IC50 of 3.47 μM. GlcN-6-P Synthase-IN-1 exhibits significant antimicrobial activity. GlcN-6-P Synthase-IN-1 has good penetration in the CNS and is able to inhibit the cytochrome P450, CYP3A4 isoform.
体外研究:
GlcN-6-P Synthase-IN-1 (Compound 4d) shows antimicrobial activity with MIC values of 1 ± 0.15, 0.5 ± 0.15, 4 ± 0.33 and 4 ± 0.33 μg/mL against S. aureus, B. subtilis, C. albicans and A. oryzae, respectively.