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编 号:F752843
分子式:C26H17N7O7
分子量:539.46
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生物活性:
VEGFR-2-IN-28 (compound 12c) is a potent VEGFR-2 inhibitor with IC50 value of 0.83 μM. VEGFR-2-IN-28 induces apoptosis and has anticancer activity.

体外研究:
VEGFR-2-IN-28 (compound 12c) (24 hours; MCF-7 cells) has anticancer activity with IC50 value of 16.50 μM.VEGFR-2-IN-28 (compound 12c) (24 hours; MCF-7 cells) prompts pre-G1 apoptosis, cell growth cessation at G2/M phase and induces apoptosis via activation of caspase-3.
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