产品
编 号：F752833
分子式：C45H57N7O7
分子量：807.98
分子式：C45H57N7O7
分子量：807.98
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 2447039-81-6
产品详情
生物活性：
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μΜ-15 μΜ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity.
体外研究：
RAS/RAS-RAF-IN-1 (compound 89; for 4 hours) has an EC50 of 0.5 μΜ-5.0 μΜ for BRAF-GTP-KRAS-G12C disruption and has an IC50 of 1.0 μΜ-10 μΜ for pERK inhibition in H358 cells.
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μΜ-15 μΜ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity.
体外研究：
RAS/RAS-RAF-IN-1 (compound 89; for 4 hours) has an EC50 of 0.5 μΜ-5.0 μΜ for BRAF-GTP-KRAS-G12C disruption and has an IC50 of 1.0 μΜ-10 μΜ for pERK inhibition in H358 cells.
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