产品
编 号：F752791
分子式：C24H15N5O4S2
分子量：501.54
分子式：C24H15N5O4S2
分子量：501.54
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CAS No: 2444363-11-3
产品详情
生物活性：
EGFR/HER2/TS-IN-1 (Compound 4d) is an EGFR, HER2 and TS (Thymidylate synthase) inhibitor with IC50 values of 0.203, 0.088 and 0.168 μM against EGFR, HER2 and TS, respectively. EGFR/HER2/TS-IN-1 induces MCF7 cell apoptosis.
体外研究：
EGFR/HER2/TS-IN-1 (Compound 4d) shows cytotoxicity with an IC50 of 0.693 μM against MCF7 cells.EGFR/HER2/TS-IN-1 (10 μg, 24 h) arrests cell cycle at G2/M phase and induces cell apoptosis in MCF7 cells.
EGFR/HER2/TS-IN-1 (Compound 4d) is an EGFR, HER2 and TS (Thymidylate synthase) inhibitor with IC50 values of 0.203, 0.088 and 0.168 μM against EGFR, HER2 and TS, respectively. EGFR/HER2/TS-IN-1 induces MCF7 cell apoptosis.
体外研究：
EGFR/HER2/TS-IN-1 (Compound 4d) shows cytotoxicity with an IC50 of 0.693 μM against MCF7 cells.EGFR/HER2/TS-IN-1 (10 μg, 24 h) arrests cell cycle at G2/M phase and induces cell apoptosis in MCF7 cells.
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