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编 号：F752790
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规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 2444308-95-4
产品详情
生物活性：
Regdanvimab (CT-P59) is a human monoclonal antibody that targets the receptor-binding domain of SARS-CoV-2 spike protein, blocking interaction with ACE2 for viral entry. Regdanvimab can be used for the research of COVID-19.
体内研究：
Regdanvimab (CT-P59) (5-80 mg/kg; i.p.; single dose) 可以降低小鼠 Gamma 和 Delta 株的病毒负担。Animal Model:hACE2 transgenic (TG) mice inoculated with Gamma or Delta variant
Dosage:5, 20, 40, and 80 mg/kg
Administration:Intraperitoneal injection, 8 h post-inoculation, single dose
Result:Delayed body weight loss and showed a statistically significant difference compared to the placebo group. Prevented the weight loss of the mice infected with Delta variant. Significantly inhibited the virus replication in the respiratory tract.
体外研究：
Regdanvimab (CT-P59) (0-1000 ng/mL; 72 h) 可以中和 Gamma, Delta 和 Epsilon 变体，IC50 在 161.5-1237 ng/mL。
Regdanvimab (CT-P59) is a human monoclonal antibody that targets the receptor-binding domain of SARS-CoV-2 spike protein, blocking interaction with ACE2 for viral entry. Regdanvimab can be used for the research of COVID-19.
体内研究：
Regdanvimab (CT-P59) (5-80 mg/kg; i.p.; single dose) 可以降低小鼠 Gamma 和 Delta 株的病毒负担。Animal Model:hACE2 transgenic (TG) mice inoculated with Gamma or Delta variant
Dosage:5, 20, 40, and 80 mg/kg
Administration:Intraperitoneal injection, 8 h post-inoculation, single dose
Result:Delayed body weight loss and showed a statistically significant difference compared to the placebo group. Prevented the weight loss of the mice infected with Delta variant. Significantly inhibited the virus replication in the respiratory tract.
体外研究：
Regdanvimab (CT-P59) (0-1000 ng/mL; 72 h) 可以中和 Gamma, Delta 和 Epsilon 变体，IC50 在 161.5-1237 ng/mL。
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