产品
编 号：F752570
分子式：C25H24ClFN6O6S
分子量：591.01
分子式：C25H24ClFN6O6S
分子量：591.01
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CAS No: 2418022-85-0
产品详情
生物活性：
TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells.
体外研究：
TMX-2164 (5 μM; 30 h; HEK293T-cells) displays sustained target engagement and to prolongs occupancy on BCL6 protein.TMX-2164 (6.2 μM; 1, 3, and 5 d; SU-DHL-4 cells) exhibits single digit micromolar antiproliferative activity in SU-DHL-4 cells.
TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells.
体外研究：
TMX-2164 (5 μM; 30 h; HEK293T-cells) displays sustained target engagement and to prolongs occupancy on BCL6 protein.TMX-2164 (6.2 μM; 1, 3, and 5 d; SU-DHL-4 cells) exhibits single digit micromolar antiproliferative activity in SU-DHL-4 cells.
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