产品
编 号：F752568
分子式：C24H24BrN5O3S2
分子量：574.51
分子式：C24H24BrN5O3S2
分子量：574.51
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CAS No: 2417995-10-7
产品详情
生物活性：
COX-2-IN-24 is an orally active inhibitor of COX-2 with IC50 value of 0.17 μM, shows anti-inflammatory and low ulcerogenic activities.
体内研究：
COX-2-IN-24 (Intraperitoneal injection; 9mg/100g; once an hour; 4 hours) shows anti-inflammatory activity in the carrageenan-induced rat paw edema model.COX-2-IN-24 (Oral gavage; 9mg/100g; oncea day; 3 days) shows low ulcerogenic activity in the received 1% gum acacia (suspending vehicle) orally male albino rats model .Animal Model:Mature male albino rats
Dosage:9mg/100g
Administration:Intraperitoneal injection; 9mg/100g; once an hour; 4 hours
Result:Exhibited a promising anti-inflammatory activity in the carrageenan-induced rat paw edema model.
Animal Model:Mature male albino rats
Dosage:9mg/100g
Administration:Oral gavage; 9mg/100g; once a day; 3 days
Result:Exhibited low ulcerogenic activity in the received 1% gum acacia (suspending vehicle) orally male albino rats model.
COX-2-IN-24 is an orally active inhibitor of COX-2 with IC50 value of 0.17 μM, shows anti-inflammatory and low ulcerogenic activities.
体内研究：
COX-2-IN-24 (Intraperitoneal injection; 9mg/100g; once an hour; 4 hours) shows anti-inflammatory activity in the carrageenan-induced rat paw edema model.COX-2-IN-24 (Oral gavage; 9mg/100g; oncea day; 3 days) shows low ulcerogenic activity in the received 1% gum acacia (suspending vehicle) orally male albino rats model .Animal Model:Mature male albino rats
Dosage:9mg/100g
Administration:Intraperitoneal injection; 9mg/100g; once an hour; 4 hours
Result:Exhibited a promising anti-inflammatory activity in the carrageenan-induced rat paw edema model.
Animal Model:Mature male albino rats
Dosage:9mg/100g
Administration:Oral gavage; 9mg/100g; once a day; 3 days
Result:Exhibited low ulcerogenic activity in the received 1% gum acacia (suspending vehicle) orally male albino rats model.
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