产品
编 号：F752567
分子式：C24H25N5O3S2
分子量：495.62
分子式：C24H25N5O3S2
分子量：495.62
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CAS No: 2417995-08-3
产品详情
生物活性：
COX-2-IN-23 (compound 9a) is a selective COX-2 inhibitor with IC50 values of 0.28 and 20.14 μM for COX-2 and COX-1. COX-2-IN-23 has anti-inflammatory activity and low ulcerogenic activity.
体内研究：
COX-2-IN-23 (compound 9a) (9 mg/kg; a single i.p.; 0-4 hours) exhibits anti-inflammatory activities and lowest incidence of pepticulcer.Animal Model:Mature male albino rats
Dosage:9 mg/kg
Administration:Intraperitoneal injection; 0, 1, 2, 3 and 4 hours.
Result:Had similar ulcerogenic activity to celecoxib.
COX-2-IN-23 (compound 9a) is a selective COX-2 inhibitor with IC50 values of 0.28 and 20.14 μM for COX-2 and COX-1. COX-2-IN-23 has anti-inflammatory activity and low ulcerogenic activity.
体内研究：
COX-2-IN-23 (compound 9a) (9 mg/kg; a single i.p.; 0-4 hours) exhibits anti-inflammatory activities and lowest incidence of pepticulcer.Animal Model:Mature male albino rats
Dosage:9 mg/kg
Administration:Intraperitoneal injection; 0, 1, 2, 3 and 4 hours.
Result:Had similar ulcerogenic activity to celecoxib.
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