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编 号:F752525
分子式:C28H22ClN5OS
分子量:512.03
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生物活性:
Enpp-1-IN-13 (Compound 1a) is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor with IC50 values of 1.29 μM and 20.2 μM against ENPP1 and ENPP3, respectively. Enpp-1-IN-13 shows anticancer activity.

体外研究:
Enpp-1-IN-13 (Compound 1a) (100 μM) shows cytotoxic effect with inhibition of 23.0 ± 2.2%, 35.1 ± 0.8% and 30.4 ± 0.1% against HeLa, MCF-7 and 1321N1 cells, respectively.
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