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编 号:F752512
分子式:C23H30N2O2
分子量:366.5
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生物活性:
AChE/BChE-IN-6 (compound 22) is a potent dual AChE/BChE inhibitor with IC50 values of 0.809 μM, 2.248 μM and > 100 μM for hBChE, hAChE and hMAO-B, respectively. AChE/BChE-IN-6 penetrates the blood-brain barrier (BBB). AChE/BChE-IN-6 can be used for Alzheimer’s disease (AD) research.

体外研究:
AChE/BChE-IN-6 (compound 22) (1-100 μM; 48 hours) can cross the blood-brain barrier and has neuroprotective to human neuronal-like SH-SY5Y and liver HepG2 cells.
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