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编 号：F752458
分子式：C26H21FN6O5
分子量：516.48
分子式：C26H21FN6O5
分子量：516.48
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CAS No: 2415291-03-9
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c-Met-IN-10 (compound 26a) is a highly potent c-Met kinase inhibitor with an IC50 value of 16 nM. c-Met-IN-10 has inhibitory activity against cancer cells A549, H460 and HT-29 with IC50s of 0.56 ~ 1.59 μM. c-Met-IN-10 suppresses the colony formation on HT-29?cells, induces HT-29 and A549?cells apoptosis, and inhibits A549?cells motility. c-Met-IN-10 can be used for researching anticancer.
c-Met-IN-10 (compound 26a) is a highly potent c-Met kinase inhibitor with an IC50 value of 16 nM. c-Met-IN-10 has inhibitory activity against cancer cells A549, H460 and HT-29 with IC50s of 0.56 ~ 1.59 μM. c-Met-IN-10 suppresses the colony formation on HT-29?cells, induces HT-29 and A549?cells apoptosis, and inhibits A549?cells motility. c-Met-IN-10 can be used for researching anticancer.
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