产品
编 号：F752435
分子式：C27H29BrN4O4
分子量：553.45
分子式：C27H29BrN4O4
分子量：553.45
产品类型
规格
价格
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结构图
CAS No: 2414921-48-3
产品详情
生物活性：
PDE5/HDAC-IN-1 (Compound 26) is a potent phosphodiesterase 5 (PDE5) and HDAC inhibitor with IC50 values of 46.3 nM and 14.5 nM, respectively. PDE5/HDAC-IN-1 induces cell apoptosis and shows anticancer activities.
体外研究：
PDE5/HDAC-IN-1 (Compound 26) shows growth inhibition with IC50 values of 12.35, 7.19 and 11.79 μM against HT-29, HCT-116 and SW-620 cells, respectively.PDE5/HDAC-IN-1 shows cytotoxic activity with IC50 values of 1.9, 1.5, 2.5, 5.5, 9.8, 18.6, 2 and 28.2 μM against Molt 4, Sup-T1, K562, AGS, PC-3, LNCaP, T47D and CCD966SK, respectively.
PDE5/HDAC-IN-1 (Compound 26) is a potent phosphodiesterase 5 (PDE5) and HDAC inhibitor with IC50 values of 46.3 nM and 14.5 nM, respectively. PDE5/HDAC-IN-1 induces cell apoptosis and shows anticancer activities.
体外研究：
PDE5/HDAC-IN-1 (Compound 26) shows growth inhibition with IC50 values of 12.35, 7.19 and 11.79 μM against HT-29, HCT-116 and SW-620 cells, respectively.PDE5/HDAC-IN-1 shows cytotoxic activity with IC50 values of 1.9, 1.5, 2.5, 5.5, 9.8, 18.6, 2 and 28.2 μM against Molt 4, Sup-T1, K562, AGS, PC-3, LNCaP, T47D and CCD966SK, respectively.
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