产品
编 号:F752366
分子式:C11H5Cl2N3O2
分子量:282.08
产品类型
结构图
CAS No: 2413865-92-4
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产品详情
生物活性:
Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes.
体外研究:
Antibacterial agent 83 (compound 17h) 对 Newmana、USA300b、Mu50 均有抗菌作用,MIC 均为0.25 μg/mL。Antibacterial agent 83 在大鼠、小鼠和犬肝微粒体中稳定性较差。