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编 号:F752232
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CAS No: 2411526-47-9
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生物活性:
Sotevtamab (16B5) is a humanized IgG2 anti-clusterin monoclonal antibody (mAb). Sotevtamab is an inhibitor of the epithelial to mesenchymal transition. Sotevtamab can be used for cancer research.
体内研究:
Sotevtamab (10 and 50 mg/kg, i.v.) is well tolerated and shows no signs of toxicity in monkeys.
体外研究:
Sotevtamab 抑制 PANC-1 胰腺癌细胞的侵袭。