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编 号:F752127
分子式:C28H21Br2FN2O2
分子量:596.28
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生物活性:
Anticancer agent 55 is a potent anticancer agent. Anticancer agent 55 shows anticancer activity via reducing the cell viability and cell migration in a dose-dependent manner. Anticancer agent 55 induces apoptosis. Anticancer agent 55 has the potential for the research of prostate cancer and breast cancer.

体外研究:
Anticancer agent 55 (compound 3h) (0-100 μM; 48 h) inhibits cell viability with IC50s of 1.18 μM and 1.95 μM for PC-3, MCF-7 cells, respectively.Anticancer agent 55 (0, 1, 3, 10 μM; 24 h) inhibits cell migration of PC-3 cells and MCF-7 cells in a dose-dependent manner.Anticancer agent 55 (0, 1, 3, 10 μM; 12, 24 h) induces apoptosis by increases the caspase-3 activity and cleaved PARP levels.
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