产品
编 号：F752124
分子式：C40H48N14O6
分子量：820.9
分子式：C40H48N14O6
分子量：820.9
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 2408723-12-4
产品详情
生物活性：
STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonist-22 can be used as an adjuvant to boost the original protein vaccine, producing potent, broad, and long-term immune protection. STING agonist-22 can be used for SARS-CoV-2 variants and sarbecovirus diseases research.
体内研究：
STING agonist-22 (CF501) 以可接受的安全性在小鼠中稳健但短暂地激活先天免疫。Animal Model:Balb/c mice (female, six weeks old)
Dosage:20, 75?μg
Administration:Intramuscular injection
Result:Although innate immunity was activated only transiently by CF501, it should be sufficient to stimulate the required humoral and cellular immune responses. The half-life of CF501 was 0.5?h and there was no detectable CF501 in the plasma after 2?h of the injection.
体外研究：
STING agonist-22 (CF501) 导致 THP-1 细胞中先天免疫反应的快速和强烈激活。
STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonist-22 can be used as an adjuvant to boost the original protein vaccine, producing potent, broad, and long-term immune protection. STING agonist-22 can be used for SARS-CoV-2 variants and sarbecovirus diseases research.
体内研究：
STING agonist-22 (CF501) 以可接受的安全性在小鼠中稳健但短暂地激活先天免疫。Animal Model:Balb/c mice (female, six weeks old)
Dosage:20, 75?μg
Administration:Intramuscular injection
Result:Although innate immunity was activated only transiently by CF501, it should be sufficient to stimulate the required humoral and cellular immune responses. The half-life of CF501 was 0.5?h and there was no detectable CF501 in the plasma after 2?h of the injection.
体外研究：
STING agonist-22 (CF501) 导致 THP-1 细胞中先天免疫反应的快速和强烈激活。
产品资料
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