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编 号：F752121
分子式：C17H13N5O3S2
分子量：399.45
分子式：C17H13N5O3S2
分子量：399.45
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CAS No: 2408695-41-8
产品详情
生物活性：
Antibacterial agent 98 (compound g37) is a potent and orally active antibacterial agent. Antibacterial agent 98 inhibits the ATPase activity of Gyrase B and impairs Staphylococcus aureus (S. aureus ) DNA supercoiling. Antibacterial agent 98 shows antibacterial activity and not induce resistance development of MRSA (methicillin-resistant S. aureus).
体外研究：
Antibacterial agent 98 (compound g37) shows antibacterial activity with an NICs of 0.1 μg/mL for S. aureus ATCC29213 and an IC50 of 0.15 μM for GyrB.Antibacterial agent 98 shows cytotoxicity with IC50s of 55.3, 38.8 μM for HepG2, HUVEC cells, respectively.
Antibacterial agent 98 (compound g37) is a potent and orally active antibacterial agent. Antibacterial agent 98 inhibits the ATPase activity of Gyrase B and impairs Staphylococcus aureus (S. aureus ) DNA supercoiling. Antibacterial agent 98 shows antibacterial activity and not induce resistance development of MRSA (methicillin-resistant S. aureus).
体外研究：
Antibacterial agent 98 (compound g37) shows antibacterial activity with an NICs of 0.1 μg/mL for S. aureus ATCC29213 and an IC50 of 0.15 μM for GyrB.Antibacterial agent 98 shows cytotoxicity with IC50s of 55.3, 38.8 μM for HepG2, HUVEC cells, respectively.
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