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编 号：F752095
分子式：C41H50O11S3
分子量：815.02
分子式：C41H50O11S3
分子量：815.02
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CAS No: 2408050-83-7
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生物活性：
Apoptosis inducer 4 (Compound 12b) is an apoptosis inducer with anticancer activities.
体外研究：
Apoptosis inducer 4 (Compound 12b) (0-50 μM, 72 h) shows antiproliferative activities against cancer cells without obvious cytotoxicity against normal cells.Apoptosis inducer 4 (0-2 μM, 48 h) causes cell cycle arrest at S phase in K562 cells and G1 phase in HepG2 cells.Apoptosis inducer 4 (0-4 μM, 24 and 48 h) induces pyknosis in K562 cells, and induces mitochondrial membrane potentials decline.Apoptosis inducer 4 (0-2 μM, 72 h) induces apoptosis in K562 and HepG2 cells.
Apoptosis inducer 4 (Compound 12b) is an apoptosis inducer with anticancer activities.
体外研究：
Apoptosis inducer 4 (Compound 12b) (0-50 μM, 72 h) shows antiproliferative activities against cancer cells without obvious cytotoxicity against normal cells.Apoptosis inducer 4 (0-2 μM, 48 h) causes cell cycle arrest at S phase in K562 cells and G1 phase in HepG2 cells.Apoptosis inducer 4 (0-4 μM, 24 and 48 h) induces pyknosis in K562 cells, and induces mitochondrial membrane potentials decline.Apoptosis inducer 4 (0-2 μM, 72 h) induces apoptosis in K562 and HepG2 cells.
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