产品
编 号:F752089
分子式:C36H63NO5
分子量:589.89
产品类型
结构图
CAS No: 2407861-48-5
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产品详情
生物活性:
Anticancer agent 65 (compound 4c) shows excellent activity in cancer cell lines, especially A549 cells, with an IC50 of 1.07 μM. Anticancer agent 65 induces S-phase arrest in A549 cells and increases the expression level of p53 and p21. Anticancer agent 65 causes apoptosis, ROS generation and collapse of MMP in A549 cells.
体外研究:
Anticancer agent 65 (compound 4c) increases the expression of Bax and decrease that of Bcl-2.