产品
编 号：F752058
分子式：C14H10Cl2N4O3S
分子量：385.23
分子式：C14H10Cl2N4O3S
分子量：385.23
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CAS No: 2403716-19-6
产品详情
生物活性：
Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 nM. Steroid sulfatase-IN-1 shows antitumor activity in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer.
体内研究：
Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity in Breast Carcinoma Model.Animal Model:67NR mouse (Breast Carcinoma Model)
Dosage:50 mg/kg
Administration:P.o.
Result:Showed significant antitumor activity with the TGI value of 51%.
Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 nM. Steroid sulfatase-IN-1 shows antitumor activity in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer.
体内研究：
Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity in Breast Carcinoma Model.Animal Model:67NR mouse (Breast Carcinoma Model)
Dosage:50 mg/kg
Administration:P.o.
Result:Showed significant antitumor activity with the TGI value of 51%.
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