产品
编 号:F752050
分子式:C22H13ClN2OS2
分子量:420.93
产品类型
结构图
CAS No: 2402779-21-7
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生物活性:
Sirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC50 values of 1.81, 2.10 and 20.5 μg/mL against SIRT1, SIRT2 and SIRT3, respectively. Sirt1/2-IN-1 displays activity in hyperacetylation of α-tubulin protein with an IC50 of 32.05 μg/mL. Sirt1/2-IN-1 shows prominent anticancer activity.