产品
编 号:F751811
分子式:C22H28ClFN6O4S
分子量:527.01
产品类型
结构图
CAS No: 2380321-50-4
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产品详情
生物活性:
CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively. (from patent WO2019207463A1 example A93).
体外研究:
The CDK4 and CDK6 cell-based IC50s of CDK4/6-IN-5 in JEKO-1 and MV4-1 1 cells are 23.8 and 61.4 nM, respectively.