产品
编 号：F751669
分子式：C23H26ClFN4OS
分子量：461
分子式：C23H26ClFN4OS
分子量：461
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规格
价格
是否有货
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CAS No: 2375780-95-1
产品详情
生物活性：
DENV-IN-6 is a potent DENV (I-IV) inhibitor with EC50s of 17.5, 13.20, 6.8 and 11.41 μM for the inhibition of DENV (I-IV) replication, respectively. DENV-IN-6 also exhibits activity of anti-HIV-1IIIB (EC50=0.0181 μM; CC50=64.92 μM).
体外研究：
DENV-IN-6 (compound 4a) (0.04, 0.2, 1, 5, 25 μM; 5 days) shows inhibitory effect on replication of DENV (I-IV) in a dose-dependent manner (EC50s=17.5, 13.20, 6.8 and 11.41 μM, respectively).DENV-IN-6 (25 μM; 5 days) shows low toxic to Vero cells (CC50＞200 μM) and exhibits stronger inhibitory effect on DENV-III than on DENV-I, II, IV with a TI value is greater than 29.41 (Therapeutic index (TI): ratio CC50/IC50).
DENV-IN-6 is a potent DENV (I-IV) inhibitor with EC50s of 17.5, 13.20, 6.8 and 11.41 μM for the inhibition of DENV (I-IV) replication, respectively. DENV-IN-6 also exhibits activity of anti-HIV-1IIIB (EC50=0.0181 μM; CC50=64.92 μM).
体外研究：
DENV-IN-6 (compound 4a) (0.04, 0.2, 1, 5, 25 μM; 5 days) shows inhibitory effect on replication of DENV (I-IV) in a dose-dependent manner (EC50s=17.5, 13.20, 6.8 and 11.41 μM, respectively).DENV-IN-6 (25 μM; 5 days) shows low toxic to Vero cells (CC50＞200 μM) and exhibits stronger inhibitory effect on DENV-III than on DENV-I, II, IV with a TI value is greater than 29.41 (Therapeutic index (TI): ratio CC50/IC50).
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