产品
编 号：F751616
分子式：C26H23FN4O
分子量：426.49
分子式：C26H23FN4O
分子量：426.49
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CAS No: 2374139-68-9
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生物活性：
P-CAB agent 1 (compound B19) is a highly potent potassium-competitive acid blocker agent with an IC50 value of 60.50 nM for H+/K+-ATPase. P-CAB agent 1 has acceptable oral absorption in rats. P-CAB agent 1 can be used for researching acid-related disorders (ARDs).
体内研究：
P-CAB agent 1 has acceptable oral absorption in rats.Pharmacokinetic Parameters of P-CAB agent 1 in female Sprague-Dawley rats.IV (2 mg/kg) PO (8 mg/kg)
AUC0-∞ (ug/L*hr)519.57341.49
t1/2 (ng/mL)0.490.8
Cmax (ug/L)149.9317
F (%)16.43
P-CAB agent 1 (compound B19) is a highly potent potassium-competitive acid blocker agent with an IC50 value of 60.50 nM for H+/K+-ATPase. P-CAB agent 1 has acceptable oral absorption in rats. P-CAB agent 1 can be used for researching acid-related disorders (ARDs).
体内研究：
P-CAB agent 1 has acceptable oral absorption in rats.Pharmacokinetic Parameters of P-CAB agent 1 in female Sprague-Dawley rats.IV (2 mg/kg) PO (8 mg/kg)
AUC0-∞ (ug/L*hr)519.57341.49
t1/2 (ng/mL)0.490.8
Cmax (ug/L)149.9317
F (%)16.43
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