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编 号：F751530
分子式：C14H9N3O5
分子量：299.24
分子式：C14H9N3O5
分子量：299.24
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CAS No: 2364493-24-1
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生物活性：
Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18，0.70，1.40，44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively.
体外研究：
Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages.Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages.Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB.
Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18，0.70，1.40，44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively.
体外研究：
Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages.Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages.Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB.
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