产品
编 号:F751484
分子式:C27H26F3NO3
分子量:469.5
产品类型
结构图
CAS No: 2360909-50-6
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产品详情
生物活性:
PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor.
体内研究:
PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) exhibits TGI(%) of 19.96% in the subcutaneous 4T1 murine breast cancer model in BALB/c mice.PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) dose-dependently inhibits tumor growth in the Bl6F10 models with TGI% of 35.59% (30 mg/kg), 38.87% (60 mg/kg) and 47.35% (120 mg/kg), respectively.