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编 号:F751458
分子式:C40H38F3N7O5S
分子量:785.83
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生物活性:
Trypanothione synthetase-IN-1 (Compound 1) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 14.8 μM when triamine spermidine is as polyamine S.

体外研究:
Trypanothione synthetase-IN-1 (Compound 1) (0-75 μM; 24 or 72 h) shows leishmanicidal activity with cytotoxicity.Trypanothione synthetase-IN-1 competes with ATP and the polyamine substrate for binding to LiTryS.
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