产品
编 号：F751439
分子式：C23H25N3O3
分子量：391.46
分子式：C23H25N3O3
分子量：391.46
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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结构图
CAS No: 2351843-48-4
产品详情
生物活性：
RAS inhibitor Abd-7, a potent RAS-binding compound (Kd=51 nM), is a RAS-effector protein-protein interaction (PPI) inhibitor. RAS inhibitor Abd-7 interacts with RAS inside the cells, prevents RAS-effector interactions and inhibits endogenous RAS-dependent signaling. RAS inhibitor Abd-7 impairs the PPI of various mutant KRAS proteins with PI3K, CRAF and RALGDS as well as NRAS Q61H and HRAS G12V.
体外研究：
RAS inhibitor Abd-7 (0 -20 μM；24-48 小时) 是一种细胞强效抑制剂，在个位数到低微摩尔范围内影响癌细胞系的活力。
RAS inhibitor Abd-7, a potent RAS-binding compound (Kd=51 nM), is a RAS-effector protein-protein interaction (PPI) inhibitor. RAS inhibitor Abd-7 interacts with RAS inside the cells, prevents RAS-effector interactions and inhibits endogenous RAS-dependent signaling. RAS inhibitor Abd-7 impairs the PPI of various mutant KRAS proteins with PI3K, CRAF and RALGDS as well as NRAS Q61H and HRAS G12V.
体外研究：
RAS inhibitor Abd-7 (0 -20 μM；24-48 小时) 是一种细胞强效抑制剂，在个位数到低微摩尔范围内影响癌细胞系的活力。
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