产品
编 号:F751308
产品类型
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CAS No: 2329669-72-7
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产品详情
生物活性:
Vudalimab is a potent dual PD-1 and CTLA-4 inhibitor as a fully humanized bispecific monoclonal antibody. Vudalimab targets immune checkpoint receptors PD-1 and CTLA-4 and promotes tumor-selective T-cell activation.
体内研究:
XmAb20717 (every two days, for 16 d; NSG mice engrafted with KG1a-luc followed by engraftment with huPBMCs) enhances allogeneic anti-tumor responses in mice.
体外研究:
XmAb20717 has binding avidity and contributes to T cell activation, including IL-2, CD45+ cells, and IFNγ.