产品
编 号：F751285
分子式：C26H28F3N5O3S2
分子量：579.66
分子式：C26H28F3N5O3S2
分子量：579.66
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2323623-80-7
产品详情
生物活性：
AS-85 is a potent ASH1L histone methyltransferase inhibitor (IC50=0.6 μM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the Kd value of 0.78?μM.
体外研究：
AS-85 inhibits the growth of leukemia cells (MV4;11, MOLM13, and KOPN8) harboring different MLL1 translocations, with GI50 values ranging from 5?μM to 25?μM, and demonstrates no effect in K562 leukemia cells without MLL1 translocations.
AS-85 is a potent ASH1L histone methyltransferase inhibitor (IC50=0.6 μM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the Kd value of 0.78?μM.
体外研究：
AS-85 inhibits the growth of leukemia cells (MV4;11, MOLM13, and KOPN8) harboring different MLL1 translocations, with GI50 values ranging from 5?μM to 25?μM, and demonstrates no effect in K562 leukemia cells without MLL1 translocations.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备