产品
编 号：F750979
分子式：C40H63N3O4
分子量：649.95
分子式：C40H63N3O4
分子量：649.95
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CAS No: 2304527-20-4
产品详情
生物活性：
Topoisomerase II inhibitor 12 (Compound 8c) is a topoisomerase II (topo II) inhibitor, working as a DNA non-intercalator. Topoisomerase II inhibitor 12 shows antineoplastic activity.
体外研究：
Topoisomerase II inhibitor 12 (Compound 8c) shows anti-proliferative activities with IC50 values of 8.80 ± 0.12, 7.13 ± 0.20, 6.56 ± 0.15, 10.99 ± 0.23, 10.71 ± 0.03 and 13.27 ± 0.32 μM against HepG2, HCT116, MDA-MB-231, Hela, K562 and PDLSC cells, respectively.
Topoisomerase II inhibitor 12 (Compound 8c) is a topoisomerase II (topo II) inhibitor, working as a DNA non-intercalator. Topoisomerase II inhibitor 12 shows antineoplastic activity.
体外研究：
Topoisomerase II inhibitor 12 (Compound 8c) shows anti-proliferative activities with IC50 values of 8.80 ± 0.12, 7.13 ± 0.20, 6.56 ± 0.15, 10.99 ± 0.23, 10.71 ± 0.03 and 13.27 ± 0.32 μM against HepG2, HCT116, MDA-MB-231, Hela, K562 and PDLSC cells, respectively.
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