产品
编 号：F750693
分子式：C210H322N46O67
分子量：4563.06
分子式：C210H322N46O67
分子量：4563.06
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2259884-03-0
产品详情
生物活性：
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D).
体内研究：
Mazdutide (15, 30 nmol/kg; sc; 单剂量) 在饮食诱导肥胖 (DIO) 的糖尿病小鼠中，可显著减轻小鼠体重和实物摄入量。
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D).
体内研究：
Mazdutide (15, 30 nmol/kg; sc; 单剂量) 在饮食诱导肥胖 (DIO) 的糖尿病小鼠中，可显著减轻小鼠体重和实物摄入量。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备