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编 号：F750691
分子式：C35H48N2O3
分子量：544.77
分子式：C35H48N2O3
分子量：544.77
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CAS No: 2259732-60-8
产品详情
生物活性：
Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent.
体内研究：
Antibacterial agent 115 (Compound 10) (0-40 mg/kg; i.g.; seven consecutive days) shows anti-inflammatory activity.Animal Model:Kunming female mice (body weight 18–22 g), 12-O-tetradecylphorbol-13- acetate (TPA) induced ear edema mice model.
Dosage:10, 20, 40 mg/kg
Administration:Gavage, seven consecutive days
Result:Inhibited swelling of mouse ears and inhibited the expression of TNF-α, IL-1β and p65.
体外研究：
Antibacterial agent 115 (Compound 10) shows antibacterial activity with MIC values of both 2.72 μg/mL against Staphylococcus aureussubsp.aureus (ATCC 29213), Staphylococcus epidermidis (ATCC 12228) and Staphylococcus aureus (ATCC 6538).
Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent.
体内研究：
Antibacterial agent 115 (Compound 10) (0-40 mg/kg; i.g.; seven consecutive days) shows anti-inflammatory activity.Animal Model:Kunming female mice (body weight 18–22 g), 12-O-tetradecylphorbol-13- acetate (TPA) induced ear edema mice model.
Dosage:10, 20, 40 mg/kg
Administration:Gavage, seven consecutive days
Result:Inhibited swelling of mouse ears and inhibited the expression of TNF-α, IL-1β and p65.
体外研究：
Antibacterial agent 115 (Compound 10) shows antibacterial activity with MIC values of both 2.72 μg/mL against Staphylococcus aureussubsp.aureus (ATCC 29213), Staphylococcus epidermidis (ATCC 12228) and Staphylococcus aureus (ATCC 6538).
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