产品
编 号:F078024
分子式:C22H30N4O3
分子量:398.5
产品类型
结构图
CAS No: 1218816-71-7
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产品详情
生物活性:
SK1-IN-1 is a potent sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 58 nM.
体内研究:
SK1-IN-1 demonstrates significant improvement in the intrinsic clearance, particularly against human liver microsomes. SK1-IN-1 is selected for rat PK studies and demonstrates modest in oral bioavailability with acceptable half-lives in blood circulation.