产品
编 号：F750631
分子式：C16H13N3O
分子量：263.29
分子式：C16H13N3O
分子量：263.29
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 2253719-35-4
产品详情
生物活性：
SY-LB-57 is a highly potent bone morphogenetic protein (BMP) receptor signaling agonist. SY-LB-57 can be used in studies of diseases such as fractures and pulmonary arterial hypertension.
体外研究：
SY-LB-57 (0.01-1000 μM, 24 h) can significantly induce cell proliferation at concentrations below 10 μM with an IC50 value of 807.93 μM in C2C12 cells.SY-LB-57 (0.01-10 μM, 15-30 min) increases the phosphorylation of Smad protein and promotes p-Smad nuclear translocation while activates the PI3K/Akt pathway and induces cytoplasmic localization of p-Akt.SY-LB-57 (0.01-10 μM, 24 h) can induce cell cycle shift towards proliferation.
SY-LB-57 is a highly potent bone morphogenetic protein (BMP) receptor signaling agonist. SY-LB-57 can be used in studies of diseases such as fractures and pulmonary arterial hypertension.
体外研究：
SY-LB-57 (0.01-1000 μM, 24 h) can significantly induce cell proliferation at concentrations below 10 μM with an IC50 value of 807.93 μM in C2C12 cells.SY-LB-57 (0.01-10 μM, 15-30 min) increases the phosphorylation of Smad protein and promotes p-Smad nuclear translocation while activates the PI3K/Akt pathway and induces cytoplasmic localization of p-Akt.SY-LB-57 (0.01-10 μM, 24 h) can induce cell cycle shift towards proliferation.
产品资料
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