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编 号:F750486
分子式:C30H45N5O3S
分子量:555.78
产品类型
结构图
CAS No: 2247061-09-0
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生物活性:
DI-1859 is a potent, selective and covalent inhibitor of DCN1. DI-1859 inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 induces a robust increase of NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver damage.