产品
编 号：F750251
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 2241724-48-9
产品详情
生物活性：
Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection.
体内研究：
Omodenbamab (514-G3; 2.5 mg/mice and 10 mg/mice; i.v.) 在菌血症模型中保护小鼠免受 MRSA 的致死攻击。Animal Model:Balb/C mice with MRSA in a bacteremia model
Dosage:2.5 mg/mice and 10 mg/mice
Administration:Intravenous injection
Result:Increased mouse Balb/C mice with MRSA in a bacteremia model survival.
体外研究：
Omodenbamab (514-G3) 与 S. aureus 结合并使 Fc 区暴露以供 FcγR1A 受体结合。Omodenbamab (10 μg/mL; 30 min, 1.5 hr, and 2.5 hr) 支持人类血细胞对 S. aureus 的调理吞噬作用。
Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection.
体内研究：
Omodenbamab (514-G3; 2.5 mg/mice and 10 mg/mice; i.v.) 在菌血症模型中保护小鼠免受 MRSA 的致死攻击。Animal Model:Balb/C mice with MRSA in a bacteremia model
Dosage:2.5 mg/mice and 10 mg/mice
Administration:Intravenous injection
Result:Increased mouse Balb/C mice with MRSA in a bacteremia model survival.
体外研究：
Omodenbamab (514-G3) 与 S. aureus 结合并使 Fc 区暴露以供 FcγR1A 受体结合。Omodenbamab (10 μg/mL; 30 min, 1.5 hr, and 2.5 hr) 支持人类血细胞对 S. aureus 的调理吞噬作用。
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