产品
编 号:F750246
分子式:C44H63FN8O11S
分子量:931.08
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规格
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1mg
询价
询价
5mg
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产品详情
生物活性:
AUTAC1 is a MetAP2-targeting autophagy-mediated degrader (AUTAC). AUTACs contain a degradation tag and a warhead to provide target specificity. AUTAC1 contains an FBnG (p-Fluorobenzyl Guanine) and a Fumagillol moiety. Fumagillol binds covalently to MetAP2.

体外研究:
AUTAC1 (1-100 μM, 24 h) silences endogenous MetAP2 in hela cells.
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