产品
编 号:F750245
分子式:C61H81FN10O14S
分子量:1229.42
产品类型
结构图
CAS No: 2241669-08-7
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产品详情
生物活性:
AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12.
体外研究:
AUTAC1 (1-100 μM, 24 h) silences endogenous FKBP12 in hela cells.